Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy. it is thought to be a major target in cancer treatment recently. Tumor-associated macrophages (TAMs) are the most abundant immune cells in the tumor microenvironment (TME). which have a large impact on tumor development and immunotherapy. https://www.jmannino.com/quick-find-Navy-blue-maang-tikka-with-meenakari-work-and-pearl-beads-only-on-Kalki-save-big/